ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines were developed and published in 2010. The ARRIVE guidelines present a 20-point list of items which must be reported in publications which have used animals in scientific research, including sample size calculations, explicit descriptions of the environmental enrichment employed and welfare-related assessments made during the study. Many journals now require authors to comply with the ARRIVE guidelines in the preparation of manuscripts.

Checklist.pdf Checklist.doc

CONSORT (Consolidated Standards Of Reporting Trials) is an evidence-based, minimum set of recommendations for reporting randomized trials. It offers a standard way for authors to prepare reports of trial findings, facilitating their complete and transparent reporting, reducing the influence of bias on their results, and aiding their critical appraisal and interpretation.The most recent version of the Statement—the CONSORT 2010 Statement—consists of a 25-item checklist and a participant flow diagram, along with some brief descriptive text. The checklist items focus on reporting how the trial was designed, analyzed, and interpreted; the flow diagram displays the progress of all participants through the trial. The Statement has been translated into several languages.

Checklist.pdf Checklist.doc Diagram.pdf Diagram.doc

SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 is a guideline for the minimum content of a clinical trial protocol. The 33-item SPIRIT checklist applies to protocols for all clinical trials and focuses on content rather than format. The checklist recommends a full description of what is planned; it does not prescribe how to design or conduct a trial. By providing guidance for key content, the SPIRIT recommendations aim to facilitate the drafting of high-quality protocols. Adherence to SPIRIT would also enhance the transparency and completeness of trial protocols for the benefit of investigators, trial participants, patients, sponsors, funders, research ethics committees or institutional review boards, peer reviewers, journals, trial registries, policymakers, regulators, and other key stakeholders.

Checklist.pdf Checklist.doc Figure.pdf Figure.doc

TIDieR (Template for Intervention Description and Replication) is a 12 item checklist for reporting details of the intervention elements (and where relevant, comparison elements) of a study. For authors of reports of randomized trials, it is recommended that TIDieR is used in conjunction with the CONSORT checklist: when authors complete item 5 of the CONSORT checklist, they should insert “refer to TIDieR checklist” and provide a separate completed TIDieR checklist. Similarly, for authors submitting protocols of trials, the TIDieR checklist can be referred to when dealing with item 11 of the SPIRIT 2013 checklist (although TIDieR items 10 and 12 are not applicable to protocols as they cannot be completed until the study is complete).The TIDieR guide provides, for each item, an explanation, elaboration, and examples of good reporting.

Checklist.pdf Checklist.docx

DoH(Declaration of Helsinki) is a set of ethical principles regarding human experimentation developed for the medical community by the World Medical Association (WMA). It is widely regarded as the cornerstone document on human research ethics. It is not a legally binding instrument under the international law, but instead draws its authority from the degree to which it has been codified in, or influenced, national or regional legislation and regulations. The most recent iteration of Helsinki (2013) was reflective of the controversy regarding the standard of care that arose from the vertical transmission trials. The seventh revised declaration of 2013 also highlights the need to disseminate research results, including negative and inconclusive studies and also includes a requirement for treatment and compensation for injuries related to research.

Declaration.pdf