Previous studies showed that curcumin encapsulated in dendrosome, a diblock nanostructure made by oleic acid (OA) and polyethylene glycol (PEG, 400 Dalton), have anticancer effects for cells through apoptosis pathway and can reduce tumor size.
The invention includes the synthesis of the non-ionic natural polymeric carriers to increasing the solubility of alpha-solanine for treatment of cancers.
It is a new type of the polymeric carrier based on the herbal fat acids that has ability for stabilizing solanine in an aqueous phosphate buffer solution at the 80 nm sizes for at least one year. This can increase solanine effects in cancer therapy together decrease dose and toxicity effects of solanine...